4-(3',5'-二溴-4-羥基苯基)氨基-6,7-二甲氧基喹唑啉抑制劑WHI-P97 is a rationally designed potent inhibitor of JAK-3. IC50 value: Target: JAK3 Treatment of mast cells with WHI-P97 inhibited the translocation of 5-lipoxygenase (5-LO) from the nucleoplasm to the nuclear membrane
